By cdsindogs.com
Researchers believe Cognitive Dysfunction Syndrome (CDS) is caused by physical and chemical changes that affect the brain function in older dogs. Dogs with CDS may show signs of confusion and/or various other behavioral changes that are not a normal part of aging.
This confusion can lead to a life of lonely isolation, separated from family members who have come to cherish their older dog's companionship. This can be as hard on family members as it is on the dog. Pet owners often describe their dogs as less responsive, forgetful or confused.
In one study at the University of California-Davis, 62% of 11- to 16-year-old dogs showed signs in at least one category of CDS. In a pet owner survey, nearly half of dogs age 8 and older showed at least one sign associated with CDS.
References:
1. Neilson JC, Hart BL, Ruehl WW: Cited in Hart BL, Hart LA: Selecting, raising and caring for dogs to avoid problem aggression. JAVMA, 210(8):1129-1134; 1997.
2. Ruehl WW, Hart BL: Canine Cognitive Dysfunction. In Psychopharmacology of Animal Behavior Disorders (Dodman NH, Schuster L, eds.). Boston: Blackwell Scientific, 1998; pp. 283-304.
3. Proprietary market research, 1998. Pet owner sample size: 255. Data on file, Zoetis.
Researchers believe Cognitive Dysfunction Syndrome (CDS) is caused by physical and chemical changes that affect the brain function in older dogs. Dogs with CDS may show signs of confusion and/or various other behavioral changes that are not a normal part of aging.
This confusion can lead to a life of lonely isolation, separated from family members who have come to cherish their older dog's companionship. This can be as hard on family members as it is on the dog. Pet owners often describe their dogs as less responsive, forgetful or confused.
In one study at the University of California-Davis, 62% of 11- to 16-year-old dogs showed signs in at least one category of CDS. In a pet owner survey, nearly half of dogs age 8 and older showed at least one sign associated with CDS.
References:
1. Neilson JC, Hart BL, Ruehl WW: Cited in Hart BL, Hart LA: Selecting, raising and caring for dogs to avoid problem aggression. JAVMA, 210(8):1129-1134; 1997.
2. Ruehl WW, Hart BL: Canine Cognitive Dysfunction. In Psychopharmacology of Animal Behavior Disorders (Dodman NH, Schuster L, eds.). Boston: Blackwell Scientific, 1998; pp. 283-304.
3. Proprietary market research, 1998. Pet owner sample size: 255. Data on file, Zoetis.
Could your dog have CDS?
You'll probably be the first to notice signs of CDS, since you're the one closest to your dog. If you notice changes in your older dog's habits or behavior, be sure to talk with your veterinarian. Above all, resist the urge to tell yourself that your dog is “just getting old.” With your help, your veterinarian can determine if the changes in your dog are associated with canine Cognitive Dysfunction Syndrome.
If your dog is over the age of 8, please take a few minutes to complete a Senior Dog CDS Checklist that you can print and take to your veterinarian.
Your veterinarian may also find useful a CDS diagnostic aid, such as the Senior Dog Behavior History Form. For diagnosis, print the form and take it to your veterinarian.
You'll probably be the first to notice signs of CDS, since you're the one closest to your dog. If you notice changes in your older dog's habits or behavior, be sure to talk with your veterinarian. Above all, resist the urge to tell yourself that your dog is “just getting old.” With your help, your veterinarian can determine if the changes in your dog are associated with canine Cognitive Dysfunction Syndrome.
If your dog is over the age of 8, please take a few minutes to complete a Senior Dog CDS Checklist that you can print and take to your veterinarian.
Your veterinarian may also find useful a CDS diagnostic aid, such as the Senior Dog Behavior History Form. For diagnosis, print the form and take it to your veterinarian.
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How can you help?
Recapturing the good times between you and your senior dog is now an exciting possibility, thanks to Anipryl® (selegiline hydrochloride, L-deprenyl hydrochloride) Tablets, the first and only drug approved by the FDA for the control of clinical signs associated with canine Cognitive Dysfunction Syndrome. Anipryl can be prescribed by your veterinarian after a diagnosis of CDS has been determined. |
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Anipryl comes in a convenient tablet form for easy dosing. Most dogs are prescribed one tablet each day, preferably in the morning. (Anipryl can be given with food.) It's important to administer every tablet as directed, since interruption of therapy could lead to the reappearance of signs.
In studies, pet owners reported that 69% to 75% of dogs improved in at least one clinical sign after one month of Anipryl therapy. Because CDS is a syndrome (a collection of signs), no two dogs will show exactly the same signs. Response to Anipryl may vary from dog to dog.
In the blinded, placebo-controlled study, owners reported that 69% of dogs improved in at least one clinical sign after one month of Anipryl therapy, compared to 52% of placebo-treated dogs. A second open label clinical study revealed that 75% of dogs improved in at least one clinical sign after one month of Anipryl therapy. Some dogs in both studies showed increased improvement during the three-month studies, indicating that some increased improvement may be seen with continued use. However, onset, duration and magnitude of response varied with individual dogs.
In studies, pet owners reported that 69% to 75% of dogs improved in at least one clinical sign after one month of Anipryl therapy. Because CDS is a syndrome (a collection of signs), no two dogs will show exactly the same signs. Response to Anipryl may vary from dog to dog.
In the blinded, placebo-controlled study, owners reported that 69% of dogs improved in at least one clinical sign after one month of Anipryl therapy, compared to 52% of placebo-treated dogs. A second open label clinical study revealed that 75% of dogs improved in at least one clinical sign after one month of Anipryl therapy. Some dogs in both studies showed increased improvement during the three-month studies, indicating that some increased improvement may be seen with continued use. However, onset, duration and magnitude of response varied with individual dogs.
In studies, the most common side effects were vomiting, diarrhea or changes in behavior, such as hyperactivity and restlessness. Most side effects were mild to moderate. In the placebo-controlled study, most of the adverse events in dogs treated with Anipryl were also observed in placebo-treated dogs, although the rates in these dogs were lower. Consult your veterinarian before using Anipryl with other medications or with tick collars. As dogs grow older, they are likely to experience more health problems. Senior dogs should be observed more closely, because changes in normal appearance, activity and behavior all can be signs that veterinary attention may be needed. Always contact your veterinarian if you notice anything unusual in your dog's appearance or behavior.
To see product information, click here or ask your veterinarian.
Giving Your Dog a New Lease on Life
Anipryl® (selegiline hydrochloride, L-deprenyl hydrochloride) Tablets can give you the chance to brighten your dog's “golden years.” With a little extra care and attention, you and your veterinarian can help your dog live a fuller, happier life. Your dog has found a place in your family and a place in your heart. Anipryl can help return your dog to that special place. And make your good times together more than just a memory.
To see product information, click here or ask your veterinarian.
Giving Your Dog a New Lease on Life
Anipryl® (selegiline hydrochloride, L-deprenyl hydrochloride) Tablets can give you the chance to brighten your dog's “golden years.” With a little extra care and attention, you and your veterinarian can help your dog live a fuller, happier life. Your dog has found a place in your family and a place in your heart. Anipryl can help return your dog to that special place. And make your good times together more than just a memory.
